ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.
Identifieur interne : 000A16 ( Main/Exploration ); précédent : 000A15; suivant : 000A17ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.
Auteurs : Rhian M. Touyz [Royaume-Uni] ; Hongliang Li [République populaire de Chine] ; Christian Delles [Royaume-Uni]Source :
- Clinical science (London, England : 1979) [ 1470-8736 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Infections à coronavirus, Pneumopathie virale.
- métabolisme : Infections à coronavirus, Maladies cardiovasculaires, Peptidyl-Dipeptidase A, Pneumopathie virale.
- Humains, Pandémies, Système rénine-angiotensine.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Peptidyl-Dipeptidase A.
- metabolism : Cardiovascular Diseases, Coronavirus Infections, Pneumonia, Viral.
- pathology : Coronavirus Infections, Pneumonia, Viral.
- physiology : Betacoronavirus.
- Humans, Pandemics, Renin-Angiotensin System.
Abstract
Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.
DOI: 10.1042/CS20200363
PubMed: 32255491
Affiliations:
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Le document en format XML
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It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li><li>République populaire de Chine</li></country><region><li>Hubei</li><li>Écosse</li></region><settlement><li>Glasgow</li><li>Wuhan</li></settlement><orgName><li>Université de Glasgow</li></orgName></list><tree><country name="Royaume-Uni"><region name="Écosse"><name sortKey="Touyz, Rhian M" sort="Touyz, Rhian M" uniqKey="Touyz R" first="Rhian M" last="Touyz">Rhian M. Touyz</name></region><name sortKey="Delles, Christian" sort="Delles, Christian" uniqKey="Delles C" first="Christian" last="Delles">Christian Delles</name></country><country name="République populaire de Chine"><region name="Hubei"><name sortKey="Li, Hongliang" sort="Li, Hongliang" uniqKey="Li H" first="Hongliang" last="Li">Hongliang Li</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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